鬼笔环肽-赖氨酸标记

	货号	5304	存储条件	在零下15度以下保存, 避免光照
	规格	100 ug	价格	1164
	Ex (nm)		Em (nm)
	分子量	885.91	溶剂	DMSO

简要概述

产品基本信息

货号：5304

产品名称：鬼笔环肽-赖氨酸标记

规格：100ug

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：885.91

溶剂：DMSO

产品介绍

鬼笔环肽赖氨酸是一种方便的化合物，可用于开发各种鬼笔环肽衍生物，这些衍生物可用于研究细胞结构和其他生物学应用。它易于与胺反应性染料，生物素和其他标签分子（例如NHS酯，异硫氰酸酯和磺酰氯等）反应。鬼笔环肽是一种双环七肽毒素，特异性结合在F-肌动蛋白亚基之间的界面上，将相邻的亚基锁定在一起。鬼笔环肽与肌动蛋白丝的结合比与肌动蛋白单体的结合要紧密得多，从而导致肌动蛋白亚基从丝端解离的速率常数降低，从而通过防止丝解聚而基本稳定了肌动蛋白丝。鬼笔环肽的性质是研究F-肌动蛋白在细胞中分布的有用工具，方法是用荧光类似物标记鬼笔环肽并将其用于染色肌动蛋白丝以进行光学显微镜检查。已经证明，鬼笔环肽的荧光衍生物在定位活细胞或固定细胞中的肌动蛋白丝以及在体外可视化单个肌动蛋白丝方面非常有用。荧光鬼笔环肽衍生物已被用作高分辨率研究肌动蛋白网络的重要工具。 AAT Bioquest为多色成像应用提供了多种具有不同颜色的荧光鬼笔环肽衍生物。

参考文献

Hybrid elastomer-plastic microfluidic device as a convenient model for mimicking the blood-brain barrier in vitro.
Authors: Nguyen, Phuoc Quang Huy and Duong, Duong Duy and Kwun, Jun Dae and Lee, Nae Yoon
Journal: Biomedical microdevices (2019): 90

Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival.
Authors: Lin, Shelly C Y and Thorne, Peter R and Housley, Gary D and Vlajkovic, Srdjan M
Journal: Frontiers in cellular neuroscience (2019): 207

Gross anatomy of the muscle systems and associated innervation of Apatemon cobitidis proterorhini metacercaria (Trematoda: Strigeidea), as visualized by confocal microscopy.
Authors: Stewart, M T and Mousley, A and Koubková, B and Sebelová, S and Marks, N J and Halton, D W
Journal: Parasitology (2003): 273-82

Light and electron microscopic study of changes in the organization of the cortical actin cytoskeleton during chromaffin cell secretion.
Authors: Tchakarov, L E and Zhang, L and Rosé, S D and Tang, R and Trifaró, J M
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society (1998): 193-203

Responses induced by tacrine in neuronal and non-neuronal cell lines.
Authors: De Ferrari, G V and von Bernhardi, R and Calderón, F H and Luza, S C and Inestrosa, N C
Journal: Journal of neuroscience research (1998): 435-44

Expression of PAC 1, an epitope associated with two synapse-enriched glycoproteins and a neuronal cytoskeleton-associated polypeptide in developing forebrain neurons.
Authors: Willmott, T and Williamson, T L and Mummery, R and Hawkes, R B and Can, A and Gurd, J W and Gordon-Weeks, P R and Beesley, P W
Journal: Neuroscience (1994): 115-29

Vasoactive amines directly modify endothelial cells to affect polymorphonuclear leukocyte diapedesis in vitro.
Authors: Doukas, J and Shepro, D and Hechtman, H B
Journal: Blood (1987): 1563-9