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OrganRegen-Y-27632 dihydrochloride(C629401)

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OrganRegen-Y-27632 dihydrochloride(C629401)

Y-27632 dihydrochloride
货号:C629401
规格:50mg
品牌:OrganRegen
价格: 3750.00
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50mg

Y-27632 dihydrochloride

货号:C629401

规格:50mg

品牌:OrganRegen


产品介绍

DESCRIPTION

Background


Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation                                                

Storage

Powder

-20 °C

3 years

In solvent

-80°C

6 months

-20 °C

1 month

Solubility

DMSO    

33.33 mg/mL(104.07 mM; Need ultrasonic)


H2O

100 mg/mL(312.25 mM; Need ultrasonic)

BIOLOGICAL ALTIVITY

In Vitro 

[2]. 

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